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575 GENES FOUND

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Gene

 

 

Gene description

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Protein class

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Tissue

Cell

Pathology

 

 

 

 

 

 

Subcellular location

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Prognostic p-value

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LRP11Low density lipoprotein receptor-related protein 11Predicted membrane proteins
Predicted secreted proteins
MitochondriaBreast cancer: 2.31e-8
Liver cancer: 2.01e-5
Expressed in all
ZNF385BZinc finger protein 385BPredicted intracellular proteins
Nucleoli fibrillar centerRenal cancer: 1.04e-9
Breast cancer: 4.86e-8
Tissue enhanced
PGK1Phosphoglycerate kinase 1Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Breast cancer: 7.05e-8
Head and neck cancer: 2.65e-6
Cervical cancer: 2.69e-5
Liver cancer: 2.74e-4
Pancreatic cancer: 8.34e-4
Expressed in all
PCMT1Protein-L-isoaspartate (D-aspartate) O-methyltransferaseEnzymes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
CytosolBreast cancer: 4.02e-7
Head and neck cancer: 1.88e-4
Liver cancer: 2.58e-4
Endometrial cancer: 4.27e-4
Urothelial cancer: 6.38e-4
Cervical cancer: 9.58e-4
Expressed in all
TFPI2Tissue factor pathway inhibitor 2Predicted intracellular proteins
Predicted secreted proteins
Breast cancer: 8.33e-7
Endometrial cancer: 5.42e-4
Renal cancer: 8.53e-4
Tissue enriched
FAM173BFamily with sequence similarity 173, member BPredicted intracellular proteins
Predicted membrane proteins
Nucleus
Vesicles		Breast cancer: 1.32e-6
Expressed in all
IL27RAInterleukin 27 receptor, alphaPredicted membrane proteins
Vesicles
Cytosol		Renal cancer: 2.58e-10
Breast cancer: 1.74e-6
Mixed
JCHAINJoining chain of multimeric IgA and IgMPlasma proteins
Predicted secreted proteins
Head and neck cancer: 7.56e-7
Breast cancer: 1.81e-6
Renal cancer: 1.40e-4
Expressed in all
ARID5AAT rich interactive domain 5A (MRF1-like)Predicted intracellular proteins
Transcription factors
Nucleus
Nucleoli		Renal cancer: 4.24e-8
Breast cancer: 2.05e-6
Expressed in all
MAP2K6Mitogen-activated protein kinase kinase 6Enzymes
Predicted intracellular proteins
Nucleus
Cytosol		Breast cancer: 2.27e-6
Pancreatic cancer: 7.52e-4
Mixed
NEFHNeurofilament, heavy polypeptideDisease related genes
Predicted intracellular proteins
Nucleus
Nuclear bodies
Centrosome		Breast cancer: 2.33e-6
Tissue enriched
DEF6DEF6 guanine nucleotide exchange factorPredicted intracellular proteins
NucleoplasmRenal cancer: 1.02e-8
Breast cancer: 3.02e-6
Cervical cancer: 1.08e-4
Colorectal cancer: 1.71e-4
Endometrial cancer: 2.37e-4
Mixed
C6orf141Chromosome 6 open reading frame 141Predicted intracellular proteins
Nuclear membraneBreast cancer: 3.92e-6
Endometrial cancer: 1.15e-4
Tissue enhanced
CA3Carbonic anhydrase IIIEnzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Breast cancer: 4.24e-6
Tissue enriched
GSTK1Glutathione S-transferase kappa 1Enzymes
Plasma proteins
Predicted intracellular proteins
PeroxisomesRenal cancer: 2.10e-6
Breast cancer: 4.41e-6
Expressed in all
PEX10Peroxisomal biogenesis factor 10Disease related genes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Transporters
NucleoplasmRenal cancer: 4.16e-6
Breast cancer: 4.50e-6
Expressed in all
MAL2Mal, T-cell differentiation protein 2 (gene/pseudogene)Predicted membrane proteins
Breast cancer: 4.57e-6
Renal cancer: 2.39e-5
Endometrial cancer: 8.44e-5
Pancreatic cancer: 3.98e-4
Mixed
SGK3Serum/glucocorticoid regulated kinase family, member 3Enzymes
Predicted intracellular proteins
Breast cancer: 5.52e-6
Cervical cancer: 8.28e-4
Pancreatic cancer: 9.65e-4
Expressed in all
LIMCH1LIM and calponin homology domains 1Predicted intracellular proteins
Actin filamentsRenal cancer: 3.82e-7
Breast cancer: 5.55e-6
Mixed
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptideCancer-related genes
Enzymes
Plasma proteins
Predicted intracellular proteins
MitochondriaRenal cancer: 1.43e-9
Breast cancer: 7.17e-6
Expressed in all
SLC5A8Solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8Predicted membrane proteins
Breast cancer: 9.04e-6
Renal cancer: 1.97e-4
Tissue enhanced
RTN4IP1Reticulon 4 interacting protein 1Predicted intracellular proteins
Renal cancer: 8.55e-6
Breast cancer: 9.18e-6
Mixed
RAC2Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)Disease related genes
Predicted intracellular proteins
RAS pathway related proteins
Renal cancer: 1.06e-6
Breast cancer: 1.03e-5
Expressed in all
TPD52Tumor protein D52Cancer-related genes
Predicted intracellular proteins
Predicted secreted proteins
Golgi apparatus
Cytosol		Renal cancer: 4.77e-6
Breast cancer: 1.11e-5
Expressed in all
SPDYCSpeedy/RINGO cell cycle regulator family member CPredicted intracellular proteins
Breast cancer: 1.20e-5
Tissue enhanced
PIGRPolymeric immunoglobulin receptorCancer-related genes
Plasma proteins
Predicted membrane proteins
Nucleus
Nucleoli
Cytosol		Breast cancer: 1.22e-5
Renal cancer: 5.08e-5
Endometrial cancer: 2.57e-4
Tissue enhanced
ZMYM6Zinc finger, MYM-type 6Predicted intracellular proteins
Predicted membrane proteins
NucleoplasmBreast cancer: 1.30e-5
Mixed
NFKBIANuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alphaCancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors
CytosolBreast cancer: 1.33e-5
Expressed in all
PDSS2Prenyl (decaprenyl) diphosphate synthase, subunit 2Cancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
CytosolRenal cancer: 3.75e-7
Breast cancer: 1.34e-5
Colorectal cancer: 5.74e-5
Expressed in all
TNFRSF17Tumor necrosis factor receptor superfamily, member 17Cancer-related genes
CD markers
Disease related genes
Predicted intracellular proteins
Predicted membrane proteins
Head and neck cancer: 1.58e-6
Breast cancer: 1.35e-5
Tissue enhanced
RARRES3Retinoic acid receptor responder (tazarotene induced) 3Predicted intracellular proteins
Predicted membrane proteins
Pancreatic cancer: 6.26e-6
Breast cancer: 1.35e-5
Cervical cancer: 4.00e-4
Expressed in all
ATG4AAutophagy related 4A, cysteine peptidaseEnzymes
Predicted intracellular proteins
Actin filaments
Microtubules		Breast cancer: 1.36e-5
Expressed in all
TRMT2BTRNA methyltransferase 2 homolog BEnzymes
Predicted intracellular proteins
Nucleoplasm
Nuclear bodies		Renal cancer: 2.30e-7
Breast cancer: 1.58e-5
Expressed in all
SERPINA1Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1Cancer-related genes
Candidate cardiovascular disease genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
VesiclesBreast cancer: 1.61e-5
Colorectal cancer: 5.86e-4
Tissue enriched
DCTPP1DCTP pyrophosphatase 1Enzymes
Predicted intracellular proteins
Nucleoplasm
Cytosol		Renal cancer: 9.71e-9
Breast cancer: 1.64e-5
Liver cancer: 6.28e-4
Expressed in all
NFKBIENuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilonCancer-related genes
Predicted intracellular proteins
Transcription factors
Nucleus
Nucleoli fibrillar center
Cytosol		Renal cancer: 1.37e-6
Breast cancer: 1.72e-5
Liver cancer: 3.50e-4
Urothelial cancer: 8.07e-4
Mixed
TRAPPC12Trafficking protein particle complex 12Plasma proteins
Predicted intracellular proteins
Breast cancer: 1.80e-5
Renal cancer: 2.44e-4
Pancreatic cancer: 9.15e-4
Expressed in all
XRCC4X-ray repair complementing defective repair in Chinese hamster cells 4Cancer-related genes
Predicted intracellular proteins
NucleusBreast cancer: 1.80e-5
Mixed
CD52CD52 moleculeCancer-related genes
CD markers
FDA approved drug targets
Predicted membrane proteins
Breast cancer: 1.85e-5
Endometrial cancer: 2.06e-4
Head and neck cancer: 4.45e-4
Renal cancer: 5.85e-4
Tissue enriched
RASGEF1ARasGEF domain family, member 1APredicted intracellular proteins
Golgi apparatusRenal cancer: 4.11e-7
Breast cancer: 1.86e-5
Endometrial cancer: 4.28e-4
Tissue enhanced
C6orf226Chromosome 6 open reading frame 226Predicted intracellular proteins
Nuclear specklesBreast cancer: 1.93e-5
Renal cancer: 3.35e-4
Pancreatic cancer: 5.13e-4
Expressed in all
TIMM17ATranslocase of inner mitochondrial membrane 17 homolog A (yeast)Cancer-related genes
Predicted membrane proteins
Nucleoplasm
Mitochondria		Breast cancer: 1.98e-5
Expressed in all
TIPARPTCDD-inducible poly(ADP-ribose) polymeraseEnzymes
Predicted intracellular proteins
Nucleoplasm
Microtubules
Microtubule organizing center		Breast cancer: 2.00e-5
Expressed in all
TAGLN2Transgelin 2Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Actin filaments
Cytosol		Renal cancer: 1.92e-10
Breast cancer: 2.06e-5
Liver cancer: 7.07e-5
Expressed in all
PTGES3Prostaglandin E synthase 3 (cytosolic)Enzymes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Cytosol		Liver cancer: 4.44e-6
Breast cancer: 2.15e-5
Ovarian cancer: 4.36e-4
Expressed in all
RAB5BRAB5B, member RAS oncogene familyPredicted intracellular proteins
RAS pathway related proteins
VesiclesBreast cancer: 2.24e-5
Expressed in all
CEBPDCCAAT/enhancer binding protein (C/EBP), deltaPredicted intracellular proteins
Transcription factors
NucleoplasmRenal cancer: 2.87e-7
Breast cancer: 2.28e-5
Expressed in all
FAM127CFamily with sequence similarity 127, member CPredicted intracellular proteins
Breast cancer: 2.41e-5
Stomach cancer: 3.72e-4
Mixed
CD24CD24 moleculePredicted intracellular proteins
Predicted secreted proteins
VesiclesBreast cancer: 2.44e-5
Colorectal cancer: 3.29e-4
Liver cancer: 7.58e-4
Tissue enhanced
BEND5BEN domain containing 5Predicted intracellular proteins
Nuclear speckles
Cytosol		Urothelial cancer: 8.30e-6
Breast cancer: 2.50e-5
Pancreatic cancer: 1.29e-4
Lung cancer: 1.29e-4
Mixed

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.